Abstract

MACHADO-ALBA, Jorge E.; MEDINA-MORALES, Diego Alejandro  and  PARRADO-FAJARDO, Ilsa Yadira. Acute renal failure secondary to acyclovir. Case report and literature review . Infect. [online]. 2015, vol.19, n.2, pp.88-91. ISSN 0123-9392.  https://doi.org/10.1016/j.infect.2014.06.004.

Renal excretion is one of the main mechanisms for the elimination of drugs, which makes the kidneys a frequent target of injury. Various drugs have been associated with development of acute renal failure. Acyclovir is an antiviral highly effective in the treatment of herpes virus infections and can cause acute kidney damage for crystal deposition in the distal convo-luted tubules. Here we present a case report on a patient who developed acute renal failure likely due to intravenous acyclovir administered for the treatment of facial herpes zoster.

Keywords : Acute kidney injury; Acyclovir; Abnormalities; Drug-induced; Pharmacovigilance.

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