Abstract

CHIAPPE, Alfredo et al. Malignant otitis externa with ecthyma gangrenosum in an hiv-positive patient. Infect. [online]. 2016, vol.20, n.1, pp.38-41. ISSN 0123-9392.  https://doi.org/10.1016/j.infect.2015.06.003.

Malignant otitis externa is an aggressive, infrequent and invasive infection of the external auditory canal. In some cases it leads to skull base compromise, particularly in immunocompromised individuals, including HIV-positive patients. Ecthyma gangrenosum is an unusual, localized cutaneous infection, caused mostly by Pseudomonas aeruginosa, with systemic compromise and a torpid evolution. An association between these 2 entities is even more rare. We present the case of a 37-year old woman with a history of 10 years’ HIV infection and good adherence to antiretroviral therapy. Although she had an adequate immunological and virological response, she presented at our emergency department in septic shock due to malignant otitis externa with ecthyma gangrenosum and possible haemophagocytic syndrome as a complication, with Pseudomonas aeruginosa determined to be the causative agent.

Keywords : Malignant otitis externa; Ecthyma gangrenosum; Pseudomonas aeruginosa; Human immunodeficiency virus; Antiretroviral therapy; Haemophagocytic syndrome.

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