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Infectio

Print version ISSN 0123-9392

Abstract

SERRANO-COLL, Héctor Alejandro; BELTRAN-ALZATE, Juan Camilo; BUITRAGO, Sonia Milena  and  CARDONA-CASTRO, Nora. Lepromatous leprosy and human immunodeficiency virus co-infection associated with phenomenon of Lucio versus immune reconstitution inflammatory syndrome. Infect. [online]. 2016, vol.20, n.4, pp.272-275. ISSN 0123-9392.  https://doi.org/10.1016/j.infect.2015.10.011.

Diffuse lepromatous leprosy (DLL) is a severe clinical outcome of lepromatous leprosy (LL). The aetiologic cause is believed to be different from Mycobacterium leprae. A new species, Mycobacterium lepromatosis, was identified from a group of Mexican patients with DLL, and severe leprosy reactional state type 3 (Lucio's phenomenon). However, a total sequencing of its genome is necessary to prove the existence of this new species. This is a report on a non-typical Colombian case of leprosy - HIV coinfection, associated with an immune reconstitution inflammatory syndrome clinically compatible with a leprosy reaction type 3 or Lucio's phenomenon.

Keywords : Leprosy; Lucio's phenomenon; Immune reconstitution inflammatory syndrome (IRIS); Human immunodeficiency virus (HIV); Highly active antiretroviral therapy (HAART); Mycobacterium leprae; Mycobacterium lepromatosis.

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