SciELO - Scientific Electronic Library Online

 
vol.21 issue4Disorders of bone mineral density in patients with HIV on antiretroviral treatment-Colombia Risaralda PereiraTigecycline in complicated skin and soft-tissue infection author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Article

Indicators

Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google

Share


Infectio

Print version ISSN 0123-9392

Abstract

HIGUITA-GUTIERREZ, Luis Felipe  and  JIMENEZ-QUICENO, Judy Natalia. Outbreaks of colistin resistant bacteria: systematic review. Infect. [online]. 2017, vol.21, n.4, pp.214-222. ISSN 0123-9392.  http://dx.doi.org/10.22354/in.v21i4.684.

Objetive:

Colistin has become a drug commonly used in endemic countries in resistance to carbapenems; however, with their use has emerged the resistance. The objective: of this study is to describe outbreaks by bacteria resistant to colistin

Design:

Systematic review of the literature in five databases with the criteria guide PRISMA of identification, tamization, election and inclusion.

Results:

13 outbreaks were identified in 7 different countries, 77% (n = 10) in Italy and Greece, and 61.5% (n = 8) in K. pneumoniae strains. Patients had baseline conditions, multiple comorbidities and frequent exposure to health services. Tests and susceptibility criteria were variable, the resistance mechanisms that are simultaneously with the resistant to colistin include carbapenemases and extended spectrum beta-lactamases. The predominant genotype according to MLST was the ST-258.

Conclusion:

The emergence of resistance to colistin is not limited to an age group or a specific comorbidity; however, it concentrated in countries where resistance to carbapenems is endemic. This allows alert health authorities and hospitals to establish programs of surveillance, prevention and control that enable timely detection and containment of this problem

Keywords : Disease Outbreaks; colistin; Drug Resistance.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )