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Infectio

Print version ISSN 0123-9392

Abstract

CASTRILLON SPITIA, Juan Daniel et al. Etiology and antimicrobial resistance profile in patients with urinary infection. Infect. [online]. 2019, vol.23, n.1, pp.45-51. ISSN 0123-9392.  http://dx.doi.org/10.22354/in.v23i1.755.

Introduction:

Urinary tract infection (UTI) is one of the most prevalent diseases in clinical practice.

Objective:

To identify the main etiologic agents and the frequency of antibiotic resistance by microorganisms isolated from urine culture and sensitivity in patients with IVU in a hospital primary care.

Materials and Methods.

Descriptive cross-sectional study, from a random sample of patients with UTI in La Virginia, Risaralda, from April 1, 2014 to March 31, 2015. Bacteria isolated from all processed urine cultures and the results of susceptibility were evaluated. Frequencies and proportions were established. For data analysis was used SPSS Statistics 22.

Results:

A total of 1563 urine cultures were performed in the study period, of which 329 (21.0%) showed further growth to 100,000 UFC. Higher frequencies of resistance were observed for E. coli to cephalothin (75.8%), ampicillin (72.6%) and trimethoprim/sulfamethoxazole (55.3%). In the 296 randomized patients it was found that the most common UTI was cystitis (70.3%) and 50.7% were not prescribed any antimicrobial. The use of anti-ulcer is associated with increased probability of inappropriate use of antibiotics (OR:4.28; 95% CI:1.070-17.153; p=0.04).

Conclusions:

There is a high bacterial resistance to first-line antibiotics for treatment of UTIs, suggesting the importance of identifying microorganisms and their antimicrobial susceptibility profiles to select which use better approach.

Keywords : Cephalosporins; antibacterials; Drug Resistance; Urinary System.

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