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Infectio

Print version ISSN 0123-9392

Abstract

VERA, Claudia A.; PATRON-ORDONEZ, Gino; VERASTEGUI-DIAZ, Araseli  and  MEJIA, Christian R.. Sociodemographic and physiopathological factors associated with tuberculosis of the central nervous system in a Public Hospital of Lima-Peru, 2014-2017. Infect. [online]. 2019, vol.23, n.2, pp.155-160. ISSN 0123-9392.  https://doi.org/10.22354/in.v23i2.772.

Objective:

To determine the sociodemographic and physiopathological factors of neurotuberculosis (NTB) in the patients registered in the Tuberculosis Control Program (TCP) of the Hospital Nacional Dos de Mayo.

Materials and Methods:

Analytical cross- sectional study, developed between July 2014 and 2017 July. We designed a card that included data sociodemographic, pathophysiological and the diagnostic characteristics. Were obtained prevalence ratio (RP) raw and adjusted, with 95% confidence intervals.

Results:

1038 patients participated. 16% of the entire population and 34% of the extrapulmonary tuberculosis had NTB. The most common clinical form was tuberculous meningoencephalitis (MEC TB) (96%). Within the clinical manifestations emphasized the seizures (22%), headache (20%), meningeal signs (18%) and sensory disorder (16%). The presence of NTB was associated with the diagnosis of HIV (aPR: 2.06, 95%CI: 1.53-2.76, P value <0.001), alcoholism (aPR: 1.53, 95%CI: 1.04-2.25, p value = 0.030) and female gender (aPR: 1.40, 95%CI: 1.06-1.84, p value = 0.019).

Conclusions:

The diagnosis of HIV, condition of alcoholism and the female gender are factors associated with increased frequency of NTB in the Hospital Dos de Mayo.

Keywords : Tuberculosis of the Central Nervous System; HIV; Peru.

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