Abstract

RODRIGUEZ-HERRERA, Daniela  and  PATINO-GIRALDO, Santiago. Atypical anogenital herpes simple virus infection in an hiv patient, successfully treatment with foscarnet: a case report. Infect. [online]. 2019, vol.23, n.2, pp.212-214. ISSN 0123-9392.  https://doi.org/10.22354/in.v23i2.779.

Pseudotumoral, hypertrophic, plaque-like anogenital ulcers are atypical features of herpes simplex infection. These ulcers develop treatment resistance and they appear in immunocompromised mainly those infected by human immunodeficiency virus. We present a 38 years-old man with AIDS and personal history of infiltrative squamous carcinoma of anal canal with multiple hypertrophic and exudative ulcers secondary to VHS-1 etiology without response to acyclovir neither valacyclovir at optimal doses but complete answer with 21 days of foscarnet treatment. Our case highlights the role of foscarnet in adults with HIV-HSV coinfection that don’t respond to frst line treatment in a country that doesn’t have clear treatment recommendations in these cases and with the limitations of absence of antiviral resistance test.

Keywords : Herpes Genitalis; Acquired Immunodeficiency Syndrome; Foscarnet; Drug Resistance, Microbial; Skin Ulcer.

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