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Print version ISSN 0123-9392


ARBELAEZ-VASQUEZ, Alejandra; CARRENO, Claudia; CONAZOS-RAMIREZ, Lilyan  and  CASTILLO, Andres. Implementation of the new clinical practice guideline for the detection and management of precancerous lesions of the cervix in women from the city of Cali, Colombia. Infect. [online]. 2020, vol.24, n.1, pp.20-26. ISSN 0123-9392.

Objectives of the study:

To determine the percentages of precancerous lesions in the cervix in a group of women with positive diagnostic to the DNA-HPV test.

Materials and methods:

The present study is a cross-sectional exploratory analysis of a database with information on the results of DNA-HPV tests (genotype and type of infection), cytology and colposcopy, carried out on 58 women aged 30 or older, for the period from October 2018 to February 2019.


Of the 58 women positive for the DNA-HPV test, 57% (n=33) were positive for the cervical cytology test. Of this group of women, 21% (n=7) were diagnosed LEI-negative; for LEI-BG 33% (n=11); and for LEI-AG, 45% (n=15) using the colposcopy test. HPV-16 has a higher detection frequency in the LEI-AG with 46.7% (n=7). Likewise, the genotypes that cover the Gardasil_4 vaccine were members in a greater percentage in the LEI-AG in comparison with other diagnosed histopathological types, this association being statistically significant, value of p = 0.033.


The implementation of the new clinical practice guideline for the detection and management of precancerous lesions of the cervix shows satisfactory results, the DNA-HPV detection being consistent, with the identification of cytological and histopathological abnormalities, allowing the early identification of women at risk to develop cervical cancer.

Keywords : Human Papillomavirus DNA Tests; Cytology; Colposcopy; Squamous Intraepithelial Lesions of the Cervix..

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