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Print version ISSN 0123-9392


RODRIGUEZ-VELASQUEZ, Javier et al. CD4+ temporal prediction in 80 patients with antiretroviral management from leukocyte counts. Infect. [online]. 2020, vol.24, n.2, pp.103-107. ISSN 0123-9392.


To establish a predictive methodology of CD4+ counts for clinical application in ranges of clinical interest based on the absolute leukocyte count.


From sequential values of leukocytes and CD4+ lymphocytes of nine patients, mathematical patterns were observed and applied in a blind study with 71 cases to confirm their predictive capacity, measuring percentages of specificity and sensitivity.


Five mathematical patterns were determined that predict 99% of the cases in which CD4+ counts are obtained from leukocyte counts with specificity and sensitivity values of 99%.


The mathematical patterns found between leukocytes and CD4 counts suggest that this phenomenon is practically deterministic.

Keywords : flow cytometry; HIV; CD4+ T lymphocytes.

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