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Infectio

Print version ISSN 0123-9392

Abstract

IBANEZ-DOSMAN, Juan Pablo; SALAZAR-OSPINA, Juan David; LOAIZA-BETANCURT, Santiago  and  HERNANDEZ-BOTERO, Johan Sebastián. Overview of antimicrobial resistance in urinary tract isolates from adult patients in the emergency room service of Manizales, Caldas, in 2018. Infect. [online]. 2020, vol.24, n.3, pp.149-154. ISSN 0123-9392.  https://doi.org/10.22354/in.v24i3.859.

Introduction:

patient management in emergency rooms require swift and effective clinical decisions; this includes choosing antibiotics correctly. Antimicrobial resistance impairs the adequate choice of empirical therapy, making the surveillance of utmost importance for antimicrobial stewardship programs.

Objective:

we aimed to describe the microbiological and antimicrobial resistance profile of urinary isolates obtained from adult patients of the emergency services of seven tertiary institutions in the city of Manizales, during the year 2018.

Results:

from a total of 1991 urinary tract isolates, 62% corresponded to Escherichia coli, the most common bacteria cultured from the emergency room. Susceptibility analysis revealed high resistance levels to cefazolin, trimethoprim-sulfamethoxazole, and ciprofloxacin. Resistance to nitrofurantoin, fosfomycin, and carbapenems was low for Escherichia coli isolates. Pseudomonas aeruginosa showed antimicrobial resistance levels above national averages.

Conclusions:

empirical antibiotic therapy must be tailored on a patient by patient basis, taking into account the severity of the disease, risk factors for multi-drug resistance bacteria, the institutional and local epidemiology depicted in this work. By using these results, the adjustment of empirical antimicrobial regimens for urinary tract infections could improve clinical outcomes and reduce health care costs.

Keywords : Emergencies; Drug Resistance, Microbial; Epidemiology; Public Health Surveillance; Anti-Bacterial Agents; Antimicrobial Stewardship.

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