Abstract

JOSA-MONTERO, Diego et al. Rectal colonization by Enterobacterales producing multiple carbapenemases: a co-production case report. Infect. [online]. 2021, vol.25, n.3, pp.193-196.  Epub May 15, 2021. ISSN 0123-9392.  https://doi.org/10.22354/in.v25i3.947.

The constant increase in carbapenemase-producing Enterobacterales (CPE) constitutes a public health problem worldwide, due to the impact generated on the mortality of patients. The gastrointestinal tract is the main reservoir for this microorganism, which is why, rectal colonization becomes an important risk factor for the development of subsequent infections. One of the active epidemiological surveillance strategies is the search for colonized patients through screening cultures, to detect these multi-resistant microorganisms.

We report the case of a patient, with a history of sepsis of pulmonary origin, colonized by Klebsiella pneumoniae with co-production of NDM + KPC carbapenemases and NDM carbapenemase-producing Escherichia coli. This finding is more and more frequent, which implies a challenge in its detection and diagnosis. Patient characteristics, procedures performed and microbiological findings are described.

Keywords : Carbapenemases; Enterobacterales; co-production; screening; nephelometry; immunoassay.

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