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Infectio
Print version ISSN 0123-9392
Abstract
SANCHEZ-PARDO, Santiago; OCHOA-DIAZ, Andrés and PRIETO-ORTIZ, Jhon E. Hepatic alterations in patients with HIV infection in a research center in Bogotá Colombia 2009 - 2019. Infect. [online]. 2021, vol.25, n.4, pp.250-255. Epub July 19, 2021. ISSN 0123-9392. https://doi.org/10.22354/in.v25i4.956.
Introduction:
Alterations in liver biochemistry are frequent in patients with HIV infection, the etiology is varied and includes multiple causes, liver steatosis is one of the most frequent with an estimated prevalence of 60% after the appearance of antiretroviral treatment
Objectives:
To characterize liver disorders in a series of patients with HIV infection at a research center in Bogotá Colombia during the period 2009-2019.
Materials and Methods:
Descriptive, retrospective, observational study of patients with HIV infection who attended a disease research center during the years 2009-2019. Results: 67 clinical histories were reviewed, 94% were men and 6% women with an average age of 44 years, 92.5% of the patients had use of anti-retroviral therapy and the diagnosis of HIV was known 11.7 years ago on average. The main liver diseases were HIV-Hepatitis C coinfection and fatty liver in equal percentages, 31.3%. The average HOMA index was 2.58.
Discussion:
Liver diseases are an important cause of morbidity and mortality in patients with HIV infection. Viral coinfections and fatty liver can be very frequent in our setting, unlike other studies.
Conclusions:
This is the first study locally to describe the liver disorders in patients with HIV, non-AIDS comorbidities, including fatty liver, play an important role in the disease and could behave like the general population. Hepatitis C continues to be a frequent coinfection in the HIV population.
Keywords : Fatty Liver; HIV Infections; Chronic hepatitis; Hepatitis C.