Abstract

ALVAREZ-ORTEGA, Carolina et al. Histoplasmosis and persistent methicillin-resistant Staphylococcus aureus bacteremia associated with a ventriculoperitoneal shunt: a case report. Infect. [online]. 2024, vol.28, n.2, pp.130-134.  Epub May 24, 2024. ISSN 0123-9392.  https://doi.org/10.22354/24223794.1179.

Histoplasmosis is a fungal infection caused by Histoplasma ssp. that primarily affects the respiratory system, while methicillin-resistant Staphylococcus aureus (MRSA) is a notorious antibiotic-resistant bacterium associated with severe infections. We present a case report of a 33-year-old female with history of hydrocephalus that underwent a VP shunt placement and was brought to the emergency department due to progressive muscle weakness and symptoms suggestive of systemic infection. Further evaluations revealed pachymeningitis, lung abnormalities, and diagnoses of histoplasmosis and methicillin-resistant Staphylococcus aureus (MRSA) bacteremia, which persisted for several weeks despite targeted antibiotic therapy. The bacteremia only resolved after the shunt was removed. This case underscores the importance of considering diverse etiologies, conducting timely diagnostic investigations with a complete medical history, and adopting tailored treatment approaches for complex cases involving concomitant infections.

Keywords : Histoplasmosis; Methicillin-Resistant Staphylococcus aureus; Persistent Infection; Ventriculoperitoneal Shunt; Case reports.

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