Introduction:

Persistent high-risk human papillomavirus (HPV) infections are strongly associated with cervical cancer, the leading cause of cancer-related deaths among women aged 30-59 years in Colombia. This study presents the screening results and distribution of high-risk HPV genotypes in women enrolled in the Por Ti Mujer programme in Cali, Colombia.

Materials and Methods:

A cross-sectional descriptive observational study was conducted using medical records of adult women screened using conventional cytology, high-risk HPV DNA testing, and visual inspection with acetic acid and lugol's iodine. Data were collected between January and June 2023 using the Por Ti Mujer program.

Results:

A total of 15,130 records were analyzed. Overall positivity, regardless of screening method, was 10.2%; positivity for HPV DNA was 15.2%, and positivity for cytology was 5.4%. Women aged 30-65 years and those in the contributory health insurance scheme group had higher rates of abnormal results. The most frequent high-risk HPV genotypes were 56-59-66 (21.2%), 33-39-68 (17.0%), 16 (13.8%), 33-58 (12.1%), and 52 (11.1%).

Discussion:

The HPV DNA positivity rate in the Por Ti Mujer program (15.2%) was higher than the global average (10.4%), but lower than the regional Latin American estimate (16.1%). The most prevalent genotypes were 56-59-66 and 33-39-68.

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