SciELO - Scientific Electronic Library Online

vol.14 issue4A comparative biopharmaceutical study of brands of ciprofloxacin tablets available on the Colombian market author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand



Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


Revista de Salud Pública

Print version ISSN 0124-0064


MACHADO-ALBA, Jorge E  and  MURILLO-MUNOZ, María M. Using an antibiotic sensitivity assay on urine cultures from patients attending general practice healthcare institutions in Pereira. Rev. salud pública [online]. 2012, vol.14, n.4, pp.710-719. ISSN 0124-0064.

ObjectivesDescribing the bacteria most frequently isolated from and antibiotic resistance patterns in urine cultures taken from patients attending general practice healthcare institutions in Pereira as urinary tract infections are a frequent cause for primary healthcare attention. Materials and MethodsA descriptive cross-sectional observational study of 131,608 members of the health social security system was carried out between January 1st 2010 and April 7th 2011;the bacteria isolated from urine cultures having more than 105 colony-forming units (CFU) were assessed, as were the sensitivity and antibacterial agents’ resistance results. Resistance was evaluated in line with Clinical and Laboratory Standards Institute (CLSI) parameters by means of the Kirby-Bauer disk diffusion manual method with Beckton Dickinson diagnostic disks. Results5,226 urine cultures were analysed, 1,058 of which showed uropathogengrowth. Bacterial growth was reported in 792 cultures (74.9 %), having more than 105 CFU. The most frequently isolated microorganisms wereEscherichia coli(67.2 %),Klebsiella sp(19.2 %) andEnterococcus sp(7.8 %).Escherichia colishowed high sensitivity to amoxicillin / clavulanate (100 %), nitrofurantoin (94.8 %), ceftriaxone (86.3 %), ciprofloxacin (71.0 %) and high resistance to ampicillin (54.7 %), amoxicillin (50.0 %), trimethoprim-sulfamethoxazole (43.8 %) and cephalothin (42.8 %). ConclusionsNitrofurantoin may be the best therapeutic option in first-line management of lower urinary tract infection and ciprofloxacin for pyelonephritis due to its effectiveness and low resistance as seen in primary healthcare practice in Pereira.

Keywords : Microbial sensitivity test; drug resistance; microbe; anti-bacterial agent; urinary tract infection; pyelonephritis; uropathogenicEscherichia coli.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )