Abstract

DIAZ-MERCHAN, Cristian C. et al. Quantifying polycyclic aromatichydrocarbons in urine samples taken from traffic police working in Bogota's metropolitan area. Rev. salud pública [online]. 2013, vol.15, n.2, pp.237-246. ISSN 0124-0064.

Objective Quantifying polycyclic aromatic hydrocarbon levels in urine samples taken from a population of traffic police working in the metropolitan area of Bogotá who were occupationally exposed to 1-hydroxypyrene (1-OHP) and 3-hydroxy-benzo[a]pyrene (3-BaP) metabolites from polycyclic aromatic hydrocarbons (PAH) having toxicological interest, related to their detection, and a degree of exposure to particulate material having a size less than 10 micrometres (PM₁₀) and/or other factors. Methods A cross-sectional study was made of 524 traffic police, 413 of whom were engaged in operational and 111 in administrative functions. Urine samples were taken from all the individuals included in the study for determining PAH metabolites by gas chromatography/mass spectrometry (GC/MS). The presence of factors associated with the detection of metabolites was analysed, such as smoking, consuming roasted/grilled food, place of residence and exposure to PM₁₀. The odds ratio (OR) was calculated as a measure of association. Results Higher 1-OHP and 3-BaP levels were found in exposed individuals, having a significant OR for detecting 6.3 ((3.6-11.1) 95 % CI) and 15.6 ((6.2-39) 95 % CI) metabolites, respectively. Significant OR were found for detecting PAH metabolites and exposure to PM₁₀, smoking and consuming roasted/grilled food. Discussion There was an important and significant association between work-related exposure to environmental contamination and detecting toxicologically important PAH metabolites in urine samples. Factors such as smoking, consuming freshly grilled/roasted food and exposure to PM₁₀ were also found to be positively associated with detecting such metabolites, but to a lesser extent.

Keywords : Polycyclic hydrocarbon; aromatic; biological marker; toxicology; occupational exposure; environmental pollution.

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