SciELO - Scientific Electronic Library Online

 
vol.20 issue1Factors associated with susceptibility to cigarette consumption in 10 and 11 year old school students from Cartagena, ColombiaEvaluation of the need for specialists in oncology, Bogota, Colombia, 2015 author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Article

Indicators

Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google

Share


Revista de Salud Pública

Print version ISSN 0124-0064

Abstract

MACHADO-ALBA, Jorge E. et al. Monitoring and impact of the disclosure of five health alerts for drugs in Colombia. Rev. salud pública [online]. 2018, vol.20, n.1, pp.23-26. ISSN 0124-0064.  http://dx.doi.org/10.15446/rsap.v20n1.56884.

Objective

Make the notification and monitoring compliance with five health drug alerts to a group of health care providers in Colombia.

Methods

Quasi-experimental, prospective, before-after study, without control group, by intervening in physician prescribers of ketoconazole, metoclopramide, nimesulide, diacerein, strontium ranelate. The affiliated population of the contributory system of the Colombian Health System was taken as the universe population sample from 13 health promoting entities (EPS) of Colombia. Patients receiving monthly these drugs prior to the alert were identified. An educational intervention was performed and then the rate of change in the dispensation was measured.

Results

About 26 different activities were conducted on 500 prescribers. Out of a total of 4 121 954 people, 13 979 patients were identified monthly in 2013, who received some of the five medications. Likewise, a reduction in 1,470 subjects per month (-10.5%) for 2014 was observed. The drug which achieved the greatest reduction was ketoconazole (-31.1% of cases), followed by strontium ranelate (-30.3%) and metoclopramide (-8.6%). For nimesulide (+ 0.7%) and diacerein (+ 16.4%) no favorable results were obtained.

Conclusions

Patients with potentially risky prescriptions remain in Colombia; educational pharmacovigilance interventions made after the report alerts given by drug regulatory agencies may decrease the proportion of patients using these drugs.

Keywords : Pharmacovigilance; deprescriptions; ketoconazole; metoclopramide (source: MeSH, NLM).

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )