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Revista de Salud Pública
Print version ISSN 0124-0064
Abstract
URREGO-DIAZ, José A.; TRUJILLO-TRUJILLO, Julián; MEZA-CARDENAS, Mónica and CRUZ, Óscar A.. Characterization of rifampin-resistant/multidrug-resistant tuberculosis in Colombia. Rev. salud pública [online]. 2021, vol.23, n.6, pp.1-. Epub Mar 08, 2023. ISSN 0124-0064. https://doi.org/10.15446/rsap.v23n6.98937.
Objective
To describe the population affected by rifampin-resistant/multidrug-resistant tuberculosis (RR/MDR-TB) in Colombia.
Methods
Cross-sectional study on all the patients treated for RR/MDR-TB in Colombia between 2009 and 2020, using all the official sources of information. In addition, a comparison was made between the rates of RR/MDR-TB in some higher-risk groups and average population. Finally, the variables associated to pulmonary versus extrapulmonary RR/MDR-TB and those associated to resistance to other drugs were evaluated.
Results
RR/MDR-TB cases have progressively increased during the last decade. These cases were concentrated in men (64% vs. 36%, p<0.001), middle aged adults (median: 39.5 years old; IQR: 27), and in geographic regions with higher population density (59% of cases in Antioquia, Valle del Cauca and Santiago de Cali). Also, the rate of RR/MDR-TB was 2, 10 and 200 times higher in indigenous (9.45/1 000 000 vs. 4.31/1 000 000; p=0.02), prisoners (169/1 000 000 vs. 16.9/1 000 000; p<0.001), and homeless population (21/100 000 vs. 0.1/100 000; p<0.001), respectively.
Conclusions
The increase in RR/MDR-TB cases and their concentration in higher-risk groups must be kept in mind to make better policies, a more efficient distribution of resources, and better patient care.
Keywords : Tuberculosis, multidrug-resistant; epidemiology; risk factors; Colombia; drug resistance, bacterial (source: MeSH, NLM).