Abstract

JURADO, Daniel et al. Lifestyle and colorectal cancer: A case-control study in a population of middle and low income. Univ. Salud [online]. 2015, vol.17, n.1, pp.7-17. ISSN 0124-7107.

Introduction: In Pasto Colombia, the colorectal cancer is one of the major causes of morbidity and mortality from cancer. To contribute to the primary prevention of this disease, it is necessary to do studies which help to identify the population at risk and the factors that influence its development. Objective: To analyze people's lifestyles that predispose to the development of colorectal cancer (CRC) in Pasto and so contributing to decision-making for the prevention and control of this disease. Materials and methods: An analytical observational study was conducted with a sample of 55 cases (CRC +) who were randomly selected from the database of Cancer Registry of the Municipality of Pasto and matched with 55 controls (CRC -). The relationship and strength of association between lifestyle (physical activity, alcohol and snuff) and development of CRC was identified by using a multivariate logistic regression and adjusting the model for demographic, socioeconomic and clinical covariates. Results: In the multivariate analysis, it was identified that the daily consumption of alcohol and daily cigarette smoking was a statistically significant association with the development of CRC. People with a high intake of alcohol (adjusted OR = 5.8 95% CI 1.3 to 26.7) and severe cigarette consumption (adjusted OR = 9.1 95% CI 1.7 to 70) are more likely to develop CRC than the individuals who do not drink or smoke respectively. Conclusions: The findings suggest a need to promote awareness campaigns that show the risk of developing CRC caused by improper lifestyle habits such as alcohol and snuff to the population of the municipality of Pasto.

Keywords : Colorectal cancer; physical activity; alcoholism; smoking; lifestyle.

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