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Universidad y Salud

Print version ISSN 0124-7107On-line version ISSN 2389-7066

Abstract

MEDINA-ALFONSO, Mabel Idaliana; FORERO-PULIDO, Sandra Marina  and  RAMIREZ-RUEDA, Román Yesid. Seroprevalence 1/2 HTLV in blood donors in Boyacá - Colombia between 2011 and 2013. Univ. Salud [online]. 2016, vol.18, n.2, pp.209-213. ISSN 0124-7107.

Introduction: The Human T-cell lymphotropic virus is a retrovirus found to be associated with risks of infectious dermatitis, uveitis, polymyositis, arthropathies, tropical spastic paraparesis, myeloma and T-cell lymphoma. One of the means of transmission of HTLV 1/2 is the transfusion of blood units contaminated by the virus. To prevent this kind of transmission, blood donor screening has recently become a standard in Colombia and in many other countries. Objective: To report the seroprevalence of HTLV 1/2 virus in blood donors from Boyacá between 2011 and 2013. Materials and methods: A retrospective descriptive study was performed, in which the seroprevalence of HTLV 1/2 was established in 48,782 blood donors from three blood banks in the department of Boyacá by using both chemiluminescence and western blot techniques. Results: From the screened donors, 0.23% (113 / 48,782) were seroreactive (chemiluminescence positive), 0.16% (78 / 48,782) were negative, 0.04% (21 / 48,782) were undefined and 0.03% (14 / 48,782) were seropositive by western blot. Concerning gender, seropositive donors were 0.016% (8/48,782) female and 0.012% (6 / 48,782) male. Conclusion: The prevalence of HTLV 1/2 was 0.03% which is similar to what has been found in most of the countries. The data generated in this study is the first of this kind available for Boyacá and will likely contribute to the virus epidemiology at the national level.

Keywords : Human T-cell lymphotropic virus 1; human T-cell lymphotropic virus 2; seroprevalence; blood banks; blood transfusion.

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