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Universidad y Salud

Print version ISSN 0124-7107
On-line version ISSN 2389-7066


MARCELO-CORREA, Andrea; ORDONEZ-VASQUEZ, Adriana; TRESPALACIOS, Alba Alicia  and  SUAREZ-OBANDO, Fernando. Inhibition of Erwinia chrysanthemi growth to different concentrations of folic acid: possible use of folic acid as bacteriostatic agent and fortifying of Solanum tuberosum potato. Univ. Salud [online]. 2017, vol.19, n.1, pp.140-148. ISSN 0124-7107.


The enterobacteria of the Erwinia spp genus produce disease in potatoes, which is a tuber of mass consumption. The regulation of DNA methylation can regulate the proliferation of Erwinia in such a way that the concentrations of folic acid may have an effect on the microorganism pathogenic ability. On the other hand, the folic acid prevents the appearance of neural tube defects in humans.


To evaluate folic acid as a bacteriostatic agent of Erwinia and, at the same time, as part of the fortification of mass consumption food such as the potatoes.

Materials and methods:

The biochemical characterization of the Erwinia chrysanthemi was carried out and its growth compared to different concentrations of folic acid was studied.


When increasing the concentrations of the vitamin from 0.3 µg/L up to 6.8 µg/L, the bacterial growth of Erwinia chrysanthemi is inhibited. The vitamin inhibits the growth in cultivation of Erwinia chrysanthemi and acts as a bacteriostatic agent. This aspect is of great importance given that, theoretically, if potatoes were fortified with micro-nutrient, this would act against the infectious agent and, at the same time, contribute to the adequate intake of the vitamin in the general population.

Keywords : Folic acid; Erwinia, Solanum tuberosum; bacterial growth; bacterial typing techniques.

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