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Universidad y Salud
versão impressa ISSN 0124-7107versão On-line ISSN 2389-7066
Resumo
HERNANDEZ-MARTINEZ, Alejandro e MARTINEZ-SANCHEZ, Lina María. Disseminated intravascular coagulation: A review of the topic. Univ. Salud [online]. 2018, vol.20, n.3, pp.283-291. ISSN 0124-7107. https://doi.org/10.22267/rus.182003.132.
Introduction:
Disseminated intravascular coagulation is a secondary syndrome to underlying pathologies, where localized coagulation activation and generalized inflammatory response can lead to tissue and microvascular damage. A prevalence of 10.8% has been reported in several intensive care units in Colombia. Its presentation in the context of sepsis is different depending on the type of infection.
Objective:
To conduct a review of literature of the most outstanding concepts of disseminated intravascular coagulation.
Materials and methods:
A review was made by means of the search of original articles, systematic and narrative reviews, in the PubMed and ScienceDirect databases and in the Google Scholar search engine; 80 articles were selected, of which 51 were included. Publications were taken into account in Spanish, English and French, with a publication date of less than or equal to 5 years.
Results:
The description of treatment, etiology, clinical presentation and diagnosis of Disseminated Intravascular Coagulation was made, with special emphasis on the studies on molecular markers and new therapeutic alternatives.
Conclusion:
Disseminated intravascular coagulation is a complication which contributes to increase morbidity and mortality, whose early diagnosis and treatment contribute significantly to better clinical evolution.
Palavras-chave : Disseminated intravascular coagulation; sepsis; anticoagulants.