Abstract

VALENCIA BASTO, Carlos. WOUND HEALING: PROCESS OF TISSUE REPAIR THERAPEUTIC APPROACHES. Investig. andina [online]. 2010, vol.12, n.20, pp.85-98. ISSN 0124-8146.

Introduction: the wound healing process is a sequence of events depends on the cellular dynamics of the injured and surrounding tissue, allowing the release of growth factors and cytokines to carry out the repair in three phases: acute or inflammatory, cell proliferation and tissue remodeling. Methods: we searched for articles in major scientific databases as PubMed of NCBI, Science Direct, HINARI and JSTOR. Results: related studies in this review, trying to improve and optimize the phenomenon of scarring in adult, in order to seep up the repair time and avoid the occurrence of secondary infectious processes and restoring normal process in the repair of chronic wounds. Conclusions: it is clear that the crude extracts from leaves, shells, flowers and root bark have the potential to accelerate healing events. However, it is unknown in most cases, the active metabolites and their mechanisms of action on cells and growth factors involved in the process, so further studies are required to investigate this aspect.

Keywords : wound healing; growth factors; plants; drugs therapy.

        · abstract in Spanish | Portuguese     · text in Spanish     · Spanish ( pdf )