Resumo

PINZON DUQUE, Oscar Alonso; LOPEZ-ZAPATA, Diego Fernando  e  GIRALDO T, José Carlos. Metabolic syndrome: pathophysiological approach. Investig. andina [online]. 2015, vol.17, n.31, pp.1328-1342.  Epub 21-Set-2016. ISSN 0124-8146.

Metabolic syndrome (MetS) is a disease of high global and regional prevalence, which is often associated with complications at both cardiovascular and metabolic level, becoming into a major health risk for our population. Despite controversy about the diagnosis criteria and pathophysiology, many of these mechanisms have been sufficiently studied. The aim of this review is to summarize the proposed pathophysiological mechanisms to develop MetS, including insulin resistance as the main axis.

Palavras-chave : Metabolic Syndrome X; Pathophysiology; Insulin Resistance.

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