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Investigaciones Andina
Print version ISSN 0124-8146
Abstract
SIMANCAS-ESCORCIA, Víctor and DIAZ-CABALLERO, Antonio. IMMUNOHISTOCHEMICAL EXPRESSION OF MEMBRANE PROTEIN ASSOCIATED WITH LYSOSOMES IN MICE'S AMELOBLASTS. Investig. andina [online]. 2020, vol.22, n.40, pp.141-152. Epub June 18, 2020. ISSN 0124-8146.
Introduction:
Tooth enamel formation includes morphological changes in ameloblasts. These modifications involve the active participation of cellular organelles, including lysosomes.
Objective:
To identify the lysosomal membrane protein distribution in ameloblasts.
Materials and method:
The lysosomal membrane protein type 1 (Lamp 1) was identified in continuous growth incisor from mice (7, 14 days old) and epithelial rat's cells using the immunohistochemistry technic.
Results:
A cytoplasmic Lamp 1 marker was identified in ameloblast cells during all the stages of the process, no matter the age. Lamp 1 was detected, too, in the epithelial dental cells.
Conclusion:
It is evident the expression of Lamp 1 in ameloblasts of continuous growth incisor and epithelial dental rat's cells. Next studies must be done about the functional role of Lamp 1 in tooth enamel formation.
Keywords : Ameloblasts; immunohistochemical; lysosomes; tooth enamel.