Abstract

CASTANEDA-AGUDELO, Yeison  and  PABON-VIDAL, Adriana. New permeability pathways in Plasmodium falciparum: considerations as a pharmacological target and advances in potential inhibitors. Actu Biol [online]. 2021, vol.43, n.115, e3.  Epub Jan 24, 2022. ISSN 0304-3584.  https://doi.org/10.17533/udea.acbi/v43n115a03.

In malaria, the persistent resistance to antimalarial drugs by Plasmodium falciparum constitute a problem to world public health. New Permeability Pathways (NPP) are a promissory therapeutic target, because the parasite uses them to modify the membrane of the erythrocyte and make it permeable to various nutrients needed for its growth. We present a theme review where a compilation of various studies related to NPP, its importance and its inhibitors was made.

Keywords : NPP; Plasmodium; malaria; antimalarials; erythrocyte.

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