Abstract

SALGADO-ORDOSGOITIA, Rodrigo Daniel et al. Chemical study of fraction ethyl acetate in the fungus Ganoderma lucidum, grown in agro-industrial waste. Rev. acad. colomb. cienc. exact. fis. nat. [online]. 2016, vol.40, n.157, pp.600-607. ISSN 0370-3908.  https://doi.org/10.18257/raccefyn.391.

Studies in fungi have revealed that they have a high nutritional value, proven pharmacological action of the secondary metabolites produced in their fruiting bodies, being many species studied, emphasizing among these, the macromycete Ganoderma lucidum, from which have been isolated compounds type terpenoids and its derivatives, with biological significance, showing effectiveness in the lowering blood pressure, anti-inflammatory properties, antiviral, hypoglycemic and immunoprotective. On the other hand, mushroom cultivation promotes the solution to environmental problems, since it can be done in agro-industrial wastes. The objective was to study the chemical composition of the fungus G. lucidum, grown in agro-industrial wastes and to determine differences between the metabolites obtained, with respect to those of the species of the fungus in their wild state. To do so, G. lucidum, was cultivated in agro-industrial wastes and the ethyl acetate fraction was studied, throught chromatography column thin layer chromatography, preparative thin-layer chromatography. In addition, GC-MS, NMR-¹H, IR analysis techniques were done. The results and preparative indicated that the chromatographic separation allowed the characterization of 8 compounds. In general, it can be concluded that cultivated fungus, presents a composition of secondary metabolites similar to the reported by various researchers about the species in its wild state, establishing the majority compound corresponding to the Ganoderiol B.

Keywords : Ganoderma lucidum; Cultivation; Chemical study; Secondary metabolites.

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