Abstract

GUTIERREZ-PEREIRA, Sandra; PRADA-SERRANO, Silvia; RINCON-ALVAREZ, Laura  and  VASQUEZ -TRESPALACIOS, Elsa María. Effectiveness and Efficiency of Pulmonary Surfactants in Infants with Respiratory Distress Syndrome at the Neonatal Intensive Care Unit of the Colombian Cardiovascular Foundation, January 2009 - April 2011. Rev. Gerenc. Polit. Salud [online]. 2012, vol.11, n.22, pp.67-75. ISSN 1657-7027.

To estimate the effectiveness and efficiency of pulmonary surfactants used in infants with respiratory distress syndrome at the Colombian Cardiovascular Foundation, we designed an observational, descriptive study. We analyzed the medical records of newborns hospitalized in this institution between January 2009 and April 2011 and calculated the effectiveness and efficiency indicators for each surfactant. After analyzing aggregate data, we found that the most efficient and effective medication for these patients was Survanta. It requires fewer doses per treatment, is more economical, and generates fewer days in the intensive care unit and fewer days of mechanical ventilation. In some cases, however, Infasurf was more effective than Survanta, caused less extubation failure in infants with low birth weight and fewer complications during treatment.

Keywords : respiratory distress syndrome (RDS); newborn (NB); surfactant; effectiveness and efficiency; Respiratory distress síndrome; Respiratory Distress Syndrome (Newborn); Infant; newborn; Surfactant.

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