SciELO - Scientific Electronic Library Online

vol.9 issue3Neuronal mechanisms of learning in teleost fishEffect of Acute Fluoxetine Application on a Context Fear Conditioned Task in Behaviorally Restrained Rats author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


Universitas Psychologica

Print version ISSN 1657-9267


LAREO, LEONARDO et al. Effects of Intrahypocampal Administration of the BLMP-101 Peptide on a Spatial Memory Task in Wistar Rats. Univ. Psychol. [online]. 2010, vol.9, n.3, pp.679-688. ISSN 1657-9267.

The BLMP-101 peptide has the potential features to treat memory deficiency. The herein research aimed at corroborating the results obtained in previous researches and tests conducted on the effectiveness of the peptide BLMP-101 designed by the Computational and Structural Biochemestry Unit of the Pontificia Universidad Javeriana, Colombia. However, and unlike previous researches, the objective of this paper measured the effectiveness of the BLMP-101peptide, when supplied in different dozes and through intrahipocampal application to confirm its effects to facilitate spatial memory. 31 Wistar rats were used into 4 different groups: three treatment groups and one control group. The control group was infused with saline solution, and one of the treatment groups was infused with NMDA, while the other two experimental groups were infused with different dozes of the BLMP-101peptide (0.3, 3.0 ug/ul). Results suggest that the BLMP-101 peptide, when supplied in 3.0 ug/ul, facilitates spatial memory showing better results than the NMDA.

Keywords : Peptyde (37330); Learning (28030); Learning in Rats (42860); Peptides; Learning; Rats; Psychology.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License