SciELO - Scientific Electronic Library Online

vol.39 suppl.2Microsatellite instability analysis using BAT-26 marker in patients with gastric or colorectal cancer diagnosed at Hospital Universitario de SantanderInadequate use of misoprostol. A public health problem? author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


Colombia Médica

On-line version ISSN 1657-9534


RONDON, Fernando et al. Genetic diversity in human populations of two regions from Colombia. Colomb. Med. [online]. 2008, vol.39, suppl.2, pp.52-60. ISSN 1657-9534.

Introduction: Preliminary studies have showed close relations among southwest human populations and Andean region leaving it consequences in ethnic admixe process. However, this wide process of racial admixture today it is not exist sufficient information to define structure and genetic diversity for each region and Colombian population in general. Objectives: The principal goal from this study was to determinate the genetic structure and diversity present into human populations from Andean and Southwest Colombia regions. Methods: This study was realized by characterization allelic frequencies of 12 autosomal STR's and six RFLP's of mtDNA presents in 472 individuals from three ethnics groups: Caucasoids, Afroamericans and Amerindians. Results: mtDNA haplotypes presents in Afrodescends sample was 15% and 43% typical Amerindian and African markers respectively; the genetics diversity analysis shows a value of 0.72 in Pijao indigenous, these values are close to diversity index of mestizos from Cali (0.75). AMOVA of allelic frequencies from 12 STR's shows that genetic structures don't was significatively different (FST de 0.032); in addition it's to exhibit high endogamy in mestizos from Caldas sample (0.43) and Coyaima indigenous (0.34). Conclusions: was established genetic structure for southwest Colombian population. Additionally, the results confirm the mixing process and the genetics flow among many populations groups from Andean and southwest Colombia regions.

Keywords : mtDNA; STR's; Amerindian populations; Genetics diversity; Mixed population; Genetics flow; Colombia southwest.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License