Abstract

BENAVIDES-CORDOBA, Vicente. Drug Repositioning for COVID-19. Colomb. Med. [online]. 2020, vol.51, n.2, e4279.  Epub May 07, 2020. ISSN 1657-9534.  https://doi.org/10.25100/cm.v51i2.4279.

Drug repositioning is a strategy that identifies new uses of approved drugs to treat conditions different from their original purpose. With the advance of COVID-19 and the pandemic declaration; It has become the closest alternative to reduce the advance of the virus. Antimalarial, antiviral drugs, antibiotics, glucocorticoids, monoclonal antibodies, among others, are being studied; their findings, although preliminary, could establish a starting point in the search for a solution. In this review, we present a selection of drugs, of different classes and with potential activity against COVID-19, whose trials are ongoing; and as proofs of concept, double blind, add-on event-driven, would allow proposing research that generates results in less time and preserving quality criteria for drug development and approval by regulatory agencies.

Keywords : COVID-19; drug repositioning; pandemics; drug; Therapeutic alternatives.

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