Resumo

OSORIO, Jose Henry  e  URIBE-VELASQUEZ, Luis Fernando. SEROPREVALENCE AND SEROTYPIFICATION OF CANINE LEPTOSPIROSIS IN BUENAVENTURA (VALLE DEL CAUCA). Biosalud [online]. 2009, vol.8, n.1, pp.84-89. ISSN 1657-9550.

The measurement of blood amino acids is a basic test for the detection of inherited inborn errors related to some amino acids metabolism and organic acidurias. The objective of the present study was to establish reference values for amino acids in blood of canines using tandem mass spectrometry. Blood samples from 60 normal canines over 18 moths of age (30 male and 30 female) were obtained, and dried blood spots were prepared for amino acids analysis by tandem mass spectrometry. No significant differences between sexes were found. Reference values for amino acids in canines using this technique are provided. Tandem mass spectrometry is an important tool for the diagnosis of metabolic disorders.

Palavras-chave : ESI-MS/MS; dogs; metabolism; amino acids; organic acidurias.

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