Abstract

TAVERA-SALDANA, Lina Marcela et al. Sleep-Disordered Breathing in Patients with Duchenne Muscular Dystrophy. Rev. Cienc. Salud [online]. 2025, vol.23, n.spe, e23e10.  Epub Apr 22, 2025. ISSN 1692-7273.  https://doi.org/10.12804/revistas.urosario.edu.co/revsalud/a.13812.

Duchenne muscular dystrophy is associated with sleep-related respiratory disorders and impaired respiratory gas exchange that, in the early stages, can manifest as hypoventilation, but progressively evolve, from a reduction in forced vital capacity to requiring non-invasive mechanical ventilation. In addition to sleep-related respiratory disorders, patients may experience changes in the sleep architecture, increased micro-awakenings, and decreased REM sleep (R), insomnia, restless legs syndrome, or unusual behaviors during sleep. All of this has a negative impact on the quality of life of patients and their families. In the present review, the main sleep-related respiratory disorders that occur in patients with Duchenne muscular dystrophy are described, and recommendations for their timely diagnosis and treatment are made.

Keywords : Duchenne muscular dystrophy; polysomnography, sleep; sleep disorders, sleep-related respiratory disorders.

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