Abstract

PSYRDELLIS, Mariana  and  ROMINA JUSTEL, Nadia. Use of Propranolol as a Modulator of Learning and Memory in Animal Models. Av. Psicol. Latinoam. [online]. 2016, vol.34, n.3, pp.565-585. ISSN 1794-4724.  https://doi.org/10.12804/apl34.3.2016.10.

Propranolol is a non-selective β1 and β2 adrenergic antagonist. The role of this system in memory neurotransmission has been shown in various studies, either in the encoding, consolidation, recall and reconsolidation process. The aim of this work is to review the effects of this β -blocker in different animal´s paradigms, studding the implications of the noradrenergic system in memory processes. The drug shows individual results depending on the time of application and the experimental design employed. There were analyzed the effects of the drug on the different phases of memory, in animals models with spatial task, with aversive or taste stimuli, with complex training or with single trial learning.

Keywords : propranolol; memory; learning; animal models.

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