Resumo

RESTREPO-ARANGO, Marcos et al. Major depressive disorder: a genetic view. Divers.: Perspect. Psicol. [online]. 2017, vol.13, n.2, pp.279-294. ISSN 1794-9998.  https://doi.org/10.15332/s1794-9998.2017.0002.11.

Major depressive disorder is a disease that is characterized by the presence of different symptoms, ranging from not being able to eat or sleep, to not enjoy activities that were previously pleasurable, ideas of disability and suicide. Research in the field of neurosciences and psychiatric diseases in particular, increasingly tend to seek the possible genetic origins that explain the development and progression of them. In this review of the literature, is presented what has been reported in studies, that not only describe the disease from its neurophysiological disorders, but also from the genetic and epigenetic alterations, in order to provide a better understanding of the molecular and physiopathological bases of this psychiatric pathology.

Palavras-chave : depressive disorder; major; genetics; polymorphism; physiopathology; neurotransmitter agents.

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