Abstract

CRUZ AMAYA, Jorge Mario; ERASO ACOSTA, María Fernanda  and  PEDRAZA ORDONEZ, Francisco Javier. Clinical prognosis and biological factors associated with survival in canines affected by breast neoplasms. Ces. Med. Vet. Zootec. [online]. 2015, vol.10, n.2, pp.170-178. ISSN 1900-9607.

Introduction: After the skin, breast glands are the location most commonly affected by tumors in bitches. Objectives: to evaluate the survival rate in canines affected by breast neoplasms submitted to surgery, relating the histopathological diagnosis with clinical factors of prognosis. Methodology: 52 bitches were included. The treatment established included mastectomy, previous blood and chest radiographic analysis in order to rule out metastasis. In 13 individuals, euthanasia was performed due to the advanced state of the disease. The variables analyzed were: frequency of presentation, age, reproductive history, diet, previous hormonal treatment, clinical stage, recurrence and survival. Statistical analysis of the variables was performed through analysis of variance and contingency tables based on chi-square tests (Χ²). Results: The effect of type of diagnosis on survival, age and pseudopregnancy showed significant differences (p<0.05). Opposite to this, no significant differences of the type of diagnosis on hormonal treatment, diet, early neutering and recurrence were observed. Conclusions: the determinant prognostic factor on survival was tumoral histopathological pattern (type of diagnosis). Animals with pseudopregnancy showed a higher susceptibility to suffer breast neoplasms. Benign tumors were observed in later ages than malignant.

Keywords : Breast neoplasms; canines; mastectomy; survival.

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