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Universitas Medica

versão impressa ISSN 0041-9095versão On-line ISSN 2011-0839


LASERNA, Andrés; BARAHONA-CORREA, Julián E.  e  ALBA, Luz Helena. Treatment of the Helicobacter pylori Infection: A Critical Appraisal of the Literature. Univ. Med. [online]. 2018, vol.59, n.3, pp.45-58. ISSN 0041-9095.


Helicobacter pylori (H. pylori) infection is a public health problem due to its relationship with gastric cancer. The escalation of antibiotic resistance hampers an effective eradication, despite the availability of treatment options. Methods: A review of the literature was performed in the database PubMed between 01/01/2015 and 31/31/2016.


Twenty six articles were included. Sequential therapy stands out as a first line therapy for scenarios such as Colombia. The implementation of adjuvants may have a positive impact on eradication rates. Local epidemiology and cost-effectiveness studies are scarce. The results were analized by erradication therapies, coadyuvant treatment, guidelines and outcomes non mentioned in the guidelines.


The correct use and knowledge of the different treatment options could reduce the costs for the health systems, the antibiotics resistance and could favor pathogen eradication. Further studies are required for establishing local recommendations.

Palavras-chave : Helicobacter pylori; disease management; therapeutics; disease eradication; anti-bacterial agents.

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