Abstract

HERNANDEZ-FLOREZ, Cristhian Eduardo; BELTRAN, Mónica Andrea  and  CONTRERAS, Gustavo Adolfo. Neuronal Embryonic Development: A Pathway from Proliferation to Perfection. Univ. Med. [online]. 2018, vol.59, n.3, pp.71-80. ISSN 0041-9095.  https://doi.org/10.11144/javeriana.umed59-3.dneu.

The human neuronal development requires a number of concrete steps which lead to orientation, regulation and differentiation of several brain components. They must be done to guarantee, in a very precise way, the correct organization and functioning of the neuronal structures. Neurogenesis is commonly divided into four consecutive stages: proliferation, migration, differentiation and maturation. In humans, those stages take place since the third week of prenatal life until the adult life. They also require a complex group of genetic packs and associated molecular factors, most of which have been recently discovered by the molecular biology technology. A review was made about the human neuronal and embryological development and the most relevant genetic components described by the literature so far.

Keywords : neurogenesis; embryonic and fetal development; cell migration; cell differentiation; plasticity.

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