Resumo

RIOS-HERNANDEZ, Korin Stefanía et al. Acute B-cell Lymphoblastic Leukemia in a Pediatric Patient: Case Report in the Pediatric Oncopediatrics Service of Hospital Universitario San Ignacio. Univ. Med. [online]. 2020, vol.61, n.1, pp.84-91. ISSN 0041-9095.  https://doi.org/10.11144/javeriana.umed61-1.bicl.

This is a paediatric patient diagnosed with acute lymphoblastic leukaemia (ALL) of B precursors, with two populations of different blasts characterized by flow cytometry (one population has an immunophenotype associated with Pre-B cells and another population corresponds to B-ALL). The genetic analysis in the bone marrow reported the presence of t (9; 22) (q34; q11) with BCR-ABL, DNA hyperdiploidy (> 50 chromosomes) and trisomy of chromosome 5. Given the genetic complexity, the patient was controlled weekly by flow cytometry with persistence of the tumor population corresponding to the common ALL-B, until its final remission.

Palavras-chave : acute lymphoblastic leukemia B; biclonality; flow cytometry; complex karyotype.

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