Abstract

GOMEZ-VEGA, Juan Carlos et al. Intra-arterial Chemotherapy for the Management of Retinoblastoma. Univ. Med. [online]. 2021, vol.62, n.4, pp.50-59.  Epub Sep 30, 2021. ISSN 0041-9095.  https://doi.org/10.11144/javeriana.umed62-4.quim.

Retinoblastoma is the most prevalent ocular tumor in childhood, with various clinical presentations. The main goals of treatment focus on survival and preservation of vision; however, treatment must be individualized. There are different therapeutic alternatives such as enucleation, systemic chemotherapy, radiotherapy and local therapies. Among the most recent alternatives is intra-arterial chemotherapy, which allows the direct administration of chemotherapeutic agents to intraocular malignant pathologies such as retinoblastoma through the ophthalmic artery. The objective of this article is to carry out a non-systematic review of the indications, advantages, disadvantages, technique, survival rates, costs, and complications of intra-arterial chemotherapy as a treatment for retinoblastoma.

Keywords : retinoblastoma; chemotherapy; neoplasms; eye enucleation; melphalan.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )