SciELO - Scientific Electronic Library Online

 
vol.63 número1Impact of Coffee Consumption on Lipid Profile and Dyslipidemia Risk: Protocol for an Umbrella ReviewBasuco Consumption: Relevant Aspects for its Treatment índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

  • Em processo de indexaçãoCitado por Google
  • Não possue artigos similaresSimilares em SciELO
  • Em processo de indexaçãoSimilares em Google

Compartilhar


Universitas Medica

versão impressa ISSN 0041-9095versão On-line ISSN 2011-0839

Resumo

LINCE-RIVERA, Isabella et al. Clinical and Microbiological Characterization of Pediatric Patients with Urinary Tract Infection in a Fourth-Level Hospital in Bogotá, Colombia, over a Period of Four Years. Univ. Med. [online]. 2022, vol.63, n.1, pp.49-58.  Epub 30-Dez-2021. ISSN 0041-9095.  https://doi.org/10.11144/javeriana.umed63-1.cmcp.

Introduction:

Urinary tract infection (UTI) is one of the most frequent infectious diseases in the pediatric population. There is no updated data available in literature of the pathogens responsible for complicated and uncomplicated UTI in children and their antimicrobial resistance profiles at the San Ignacio University Hospital or in the city of Bogotá.

Objective:

To carry out a demographic and clinical characterization of pediatric patients with UTI and a microbiological characterization of the resistance pattern of its main etiological agents.

Materials and methods:

A cross-sectional study was carried out with all pediatric patients under ten years of age with UTI confirmed by urine culture who came to our institution between January 2014 and December 2017. Redcap was used to register data corresponding to demographic variables, clinical manifestations, isolated microorganisms with their antibiograms, complications, and recurrence rate of UTI. Subsequently, a data analysis was performed.

Results:

A registry of 675 patients under ten years of age with urinary tract infection was obtained. The majority were females, two years old or younger and had fever as the cardinal sign of infection. A relevant comorbidity was constipation, and 15.3% of the children had a urinary tract malformation. Three-point five percent had a history of previous urological surgical intervention and 73.2% were experiencing their first UTI episode. Ninety-eight-point four percent of the infections were community acquired and, regardless of their origin, the most common isolated agent was Escherichia coli (73%). The most frequent resistance patterns were penicillinase-producing (41.5%), followed by multi-sensitive (32.1%) and cephalosporins resistance (26%). Regarding the treatment established, cephalosporins were used in 92% of the cases, especially of first (61%) and third (38%) generation.

Conclusions:

We obtained similar results to those found in older studies in Bogotá and the San Ignacio University Hospital. Characterizing our population showed us that, through 2014–2017 and compared to the previous six years, the sensitivity of Escherichia coli to first-generation cephalosporins was stable, which indicates they are still a viable treatment option in our case, according to the local resistance profile.

Palavras-chave : urinary tract infections; pediatrics; anti-bacterial agents; drug resistance; antibiogram; etiology; microbiology.

        · resumo em Espanhol     · texto em Inglês     · Inglês ( pdf )