Abstract

MOSQUERA PAZ, Manuel Santiago et al. Gastrointestinal stromal tumors: current management and report of six cases. rev. colomb. cir. [online]. 2004, vol.19, n.2, pp.116-125. ISSN 2011-7582.

We hereby report six patients with inmunohistochemical diagnosis of GIST located in different organs of the gastrointestinal tract and other areas, who were managed at our institution, except one case, starting in 2000 and followed until now in the services of hemato-oncology and surgery. The majority of these patients did not have a clear preoperative diagnosis or presented with high suspicion of a mesenchyunal tumor, complicate by a compressing mass, intestinal obstruction, or bleeding. We describe the most relevant aspects pertinent to diagnosis and pathologic classification, surgical management in the context of current literature reports, with emphasis on the ongoing controversies. Furthermore, we define our policy as a group on the basis of the literature review and the careful analysis of our limited experience.

Keywords : GIST; inmunohistochemistry; 50 high power fields; gastrointestinal hemorrhage; computerized scanography; c-Kit; smooth muscle actin.

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