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Revista Colombiana de Cirugía
Print version ISSN 2011-7582On-line version ISSN 2619-6107
Abstract
PASTOR-BONEL, Tania; NOVA-CAMACHO, Luiz; JIMENEZ-AGUERO, Raúl and ARINO-HERVAS, Itziar De. Metastatic gangliocytic paraganglioma: a rare histological entity diagnosed after duodenopancreatectomy. rev. colomb. cir. [online]. 2023, vol.38, n.3, pp.541-548. Epub Apr 29, 2023. ISSN 2011-7582. https://doi.org/10.30944/20117582.2186.
Introduction.
Gangliocytic paraganglioma is a rare histological entity, with the duodenum being its main extra-nodal location.
Clinical case.
This is a 54-year-old man who presented with abdominal pain and upper gastrointestinal bleeding. A suspicious ampuloma lesion was diagnosed, for which a pancreaticoduodenectomy was performed. In the histological analysis, the diagnosis of metastatic gangliocytic paraganglioma was confirmed by the pathognomonic presence of three cell lines (epithelial, ganglionic, and Schwann-like). Given his good prognosis associated with low chemosensitivity, he did not receive adjuvant treatment.
Results.
During follow-up, the patient did not present late complications or signs of recurrence one year after the intervention.
Conclusion.
Gangliocytic paraganglioma is a potentially malignant entity that requires a correct extension study and close long-term follow-up.
Keywords : paraganglioma; gangliocytic; duodenum; pancreaticoduodenectomy; neoplasm; metastasis of the neoplasm.
