Introduction.

The objective of this study was to describe the microbiological profile of microorganisms isolated in the cultures of patients with organ/space (OS) surgical site infection (SSI), after intra-abdominal surgeries performed at our institution.

Methods.

This is a retrospective descriptive study that included patients who developed organ/space SSI after undergoing abdominal surgery, Drainage of the intra-abdominal collection was performed culture collection and determination of the resistance profile.

Results.

89 ISO-OE patients were diagnosed between June 2020 and June 2023. 68.5% were drained, which was percutaneous in 54 patients (88.5%). The most frequent diagnoses were oncological (n=22, 36.1%), followed by cholecystitis (n=15, 24.6%) and acute appendicitis (n=13, 21.3%). The most frequently isolated microorganism was Escherichia coli (72%). Microbial resistance was identified in 45.9% of cases, specifically AmpC (14.8%), ESBL (13.1%), penicillinases (8.2%), IRT (6.6%), and KPC-type carbapenems (3.3%). Patients with a longer hospital stay had a higher percentage of microorganisms with antibiotic resistance (14 vs. 18 days; p=0.005).

Conclusions.

The antibiotic resistance identified is striking and was related to modifications in antibiotic therapy with medications reserved for severe infections. Resistance was greater in patients with prolonged hospital stay. Identifying the local epidemiology can guide treatment and impact the patient’s postoperative course.

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