Abstract

GUTIERREZ LESMES, Oscar Alexander. RESISTANCE AND SUSCEPTIBILITY OF MICROORGANISMS ISOLATED IN PATIENTS TREATED IN A TERTIARY INSTITUTION HOSPITAL, VILLAVICENCIO-COLOMBIA, 2012. Rev Cuid [online]. 2015, vol.6, n.1, pp.941-946. ISSN 2216-0973.  https://doi.org/10.15649/cuidarte.v6i1.148.

Introduction: Bacterial resistance is a significant public health problem and it is associated to the indiscriminate and irrational antibiotics use, which affects treatments effectiveness. Objective: To estimate bacterial resistance to the antibiotics through in vitro susceptibility tests results in a third level health institution at Villavicencio, Colombia. Materials and Methods: An observational study, descriptive, retrospective study was carried out. Statistical analysis was performed, calculating means for the variables susceptibility, resistance, antibiotic, microorganisms, and type of sample obtained from 485 susceptibility tests carried out using the Kirby-Bauer technique at the health institution. Results and Discussion: More frequently isolated microorganisms were: Escherichia coli, Klebsiella pneumoniae ss. Pneumoniae, Staphylococcus aureus ss. Aureus conforming 49% of total results, higher resistance reports on in vitro tests showed Serratia marcescens, Staphylococcus saprophyticus ss Saprophytic, and Enterobacter cloacae, showing a mean resistance higher than 50%, and a susceptibility lower than 40%, higher mean resistance was presented for the following antibiotics: Cefalotin 72,2%, Cefazolin 59,9%, Nitrofurantoin 54,4%, Ceftriaxone 52,7%. Conclusions: Antibiotics such as Cefalotin, Nitrofurantoin, Cefazolin and Ceftriaxone lose their therapeutic utility due to the high resistance demonstrated by the microorganisms isolated in in vitro tests; reinforcement of measurements for appropriate use of antibiotics is needed to diminish the possibility of adaptation and resistance. Bacterial resistance happens outside hospital environment evidencing the need to start infections control and surveillance in the community.

Keywords : Cross Infection; Drug Resistance; Microbial; Microbial Sensitivity Tests.

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