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Revista Cuidarte

Print version ISSN 2216-0973On-line version ISSN 2346-3414


CERQUERA CORDOBA, Ara Mercedes et al. Randomized controlled trial of a multicomponent program for informal caregivers of Alzheimer's patients. Rev Cuid [online]. 2021, vol.12, n.2, e2002.  Epub Oct 01, 2021. ISSN 2216-0973.


To evaluate the efficiency of a multicomponent plus respite care program on care burden and social support for informal caregivers of patients with major neurocognitive disorders associated with Alzheimer's disease.

Materials and Methods

A parallel randomized controlled trial was conducted with 58 caregivers who were randomly allocated to one of the following three comparison groups: a multicomponent plus respite care group (n=19), a respite care group (n=19), and a control group (n=20). Burden and social support were assessed by using the Zarit Scale and Medical Outcomes Study at baseline with a post-intervention at 5 months and follow-up at 10 months. The assessment of effects was measured by using a mixed-effects model with an unstructured covariance matrix.


Caregivers were mostly patients' children (72%), female (76%) having a mean age of 55.1 years (12) and less than secondary education (58%). A significant reduction of 13.1% (95%CI -19.3:6.9) in caregiver burden was found in the multicomponent plus respite care group, showing a sustained effect at 10 months (p<0.001). A non-significant increase of 10.8% (-1.7;23.4) in post-intervention social support was found in the multicomponent plus respite care group. However, the effects increased over time achieving an increase at 13.2% (p=0.039) at the 10-month follow-up. No significant effects on caregiver burden or social support were reported for the respite care group.


The multicomponent plus respite care group demonstrated beneficial effects on care burden and social support for Alzheimer's caregivers.

Keywords : Family Caregiver; Dementia; Social Support; Overload; Multi-Component Program.

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