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Revista Colombiana de Nefrología

versión On-line ISSN 2500-5006


RAMIREZ QUINTERO, José Ignacio et al. Hemolytic uremic syndrome atypical after kidney transplantation: a case report and literature review. Rev. colom. nefrol. [online]. 2017, vol.4, n.1, pp.74-84. ISSN 2500-5006.

Haemolytic uremic syndrome (HUS) is a clinical entity characterized by the appearance of non-immune hemolytic anemia, thrombocytopenia and acute renal failure. It is a disease belonging to the group of thrombotic microangiopathy (MAT) which are part of thrombotic thrombocytopenic purpura also (PTT) and some other MAT associated with other medical conditions formerly known as secondary MAT. Moreover, the variety known as atypical HUS (aHUS) is an ultra-orphan disease that frequently progresses to chronic renal failure (CRF) and is associated with high morbidity and mortality if not properly treated.

If a patient presents its first clinical manifestation of aHUS later receive a cadaveric renal transplant which not only makes it an even more exotic case but involves more complexity in their management is presented.

Palabras clave : Atypical hemolitic uremic síndrome; kidney transplant; plasmapheresis; tacrolimus; thrombotic microangiopathy; eculizumab.

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