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Revista Colombiana de Nefrología

On-line version ISSN 2500-5006

Abstract

MORA-BAUTISTA, Víctor Manuel. Congenital anomalies of the kidney and the urinary tract in Down syndrome children. Rev. colom. nefrol. [online]. 2018, vol.5, n.1, pp.54-60. ISSN 2500-5006.  http://dx.doi.org/10.22265/acnef.5.2.268.

Congenital anomalies of the kidney and the urinary tract are congenital diseases related to Down syndrome. There are not specific recommendations. A literature review was made using key words through scientific databases (Pubmed, Science Direct, Ovid, Scholar Google, UpToDate). CAKUT in Down syndrome include glomerulonephritis, kidney agenesis, microcysts, ectopic kidneys, hydronephrosis and hydroureter, even posterior urethral valves and anterior urethra obstruction, and hypospadias. It will be feasible thinking about performing kidney and urinary tract ultrasonography in first week of life. Urethrocystography must be done in selected cases. If urinary incontinence exists, patient has a history of urinary tract infections, vesicoureteral reflux has been diagnosed or if a decrease in glomerular filtration rate has been identified, we should check for vesical dysfunction associated to symptoms and urologic evaluation could be needed (uroflowmetry or urodynamics). It might be adequate an annual clinical follow up of kidney function.

Keywords : Down syndrome; CAKUT; diagnostic imaging.

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