Abstract

NAVARRO-QUIROZ, Roberto C. et al. Renal and digestive engagement in COVID-19 infections. Rev. colom. nefrol. [online]. 2020, vol.7, suppl.2, pp.259-272.  Epub May 14, 2021. ISSN 2500-5006.  https://doi.org/10.22265/acnef.7.supl.2.427.

Infection with Severe Acute Respiratory Syndrome (SARS-CoV-2) has caused one of the largest epidemiological emergencies in the last 10 years and its pathological effects are still studied. Due to the aforementioned, it is important to describe the mechanisms associated with renal and digestive compromise in SARS-CoV-2 infection.

The pathological mechanisms in kidney tissue and in the intestine caused by SARS-CoV-2 infection are characteristic of the viral tropism by cells of these systems and of the lymphocytic mechanisms of the lytic stage of the infection, with a continuous release of virions that favors the generation of an inflammatory environment with the consequent uncontrolled secretion of proinflammatory cytokines that lead to enteric infection of the intestine and alterations in the kidney.

Keywords : SARS-CoV-2; COVID-19; kidney diseases; coronavirus infections; gastrointestinal diseases.

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