<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0012-7353</journal-id>
<journal-title><![CDATA[DYNA]]></journal-title>
<abbrev-journal-title><![CDATA[Dyna rev.fac.nac.minas]]></abbrev-journal-title>
<issn>0012-7353</issn>
<publisher>
<publisher-name><![CDATA[Universidad Nacional de Colombia]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0012-73532017000100072</article-id>
<article-id pub-id-type="doi">10.15446/dyna.v84n200.57126</article-id>
<title-group>
<article-title xml:lang="en"><![CDATA[Effects of aeration, agitation and pH on the production of mycelial biomass and exopolysaccharide from the filamentous fungus Ganoderma lucidum]]></article-title>
<article-title xml:lang="es"><![CDATA[Efecto de la aireación, la agitación y el pH sobre la producción de biomasa micelial y exopolisacáridos del hongo filamentoso Ganoderma lucidum]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Agudelo-Escobar]]></surname>
<given-names><![CDATA[Lina María]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gutiérrez-López]]></surname>
<given-names><![CDATA[Yessica]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Urrego-Restrepo]]></surname>
<given-names><![CDATA[Sergio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
<xref ref-type="aff" rid="Aaf"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Antioquia  ]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de Antioquia  ]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad de Antioquia  ]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<aff id="Af4">
<institution><![CDATA[,CEO, Progal BT  ]]></institution>
<addr-line><![CDATA[Medellín ]]></addr-line>
<country>Colombia</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>03</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>03</month>
<year>2017</year>
</pub-date>
<volume>84</volume>
<numero>200</numero>
<fpage>72</fpage>
<lpage>79</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_arttext&amp;pid=S0012-73532017000100072&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_abstract&amp;pid=S0012-73532017000100072&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://www.scielo.org.co/scielo.php?script=sci_pdf&amp;pid=S0012-73532017000100072&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="en"><p><![CDATA[Abstract Due to the increasing demand for functional foods and dietary supplements, mushroom production has increased significantly in recent years, which is why the study of operational conditions affecting the biotechnology cultivation of these mushrooms has become the aim of numerous studies. This study attempted to know the effect of pH, agitation and aeration on the biomass and polysaccharides production of filamentous fungus Ganoderma lucidum in fermentations made in a 5L bioreactor. The results allowed to establish that a bistage pH strategy (one stage with a fixed pH control, and a second stage without control), combined with hydrodynamic stress, which involves high agitation and high aeration, favors biomass and polysaccharides production, achieving increases of up to 100% compared to that obtained with the reference conditions.]]></p></abstract>
<abstract abstract-type="short" xml:lang="es"><p><![CDATA[Resumen Debido a la creciente demanda de alimentos funcionales y suplementos dietarios, la producción de hongos ha aumentado significativamente en los últimos años, razón por la cual el estudio de las condiciones operacionales que afectan el cultivo biotecnológico de estos hongos se ha convertido en el objeto de estudio de muchos investigadores. Con esta investigación se busca evaluar el efecto que tiene el pH, la agitación y la aireación sobre la producción de biomasa y polisacáridos de un hongo filamentoso en fermentaciones realizadas en biorreactor de 5L. Los resultados permitieron establecer que una estrategia de pH escalonado que incluye dos etapas una con control a un pH fijo y una segunda etapa sin control, combinada con estrés hidrodinámico, que implica alta agitación y alta aireación, favorece la producción de biomasa y polisacáridos, alcanzando incrementos de hasta 100% comparados con los obtenido con las condiciones de referencia.]]></p></abstract>
<kwd-group>
<kwd lng="en"><![CDATA[Biotechnological culture]]></kwd>
<kwd lng="en"><![CDATA[fungi submerged culture]]></kwd>
<kwd lng="en"><![CDATA[Exopolysaccharides]]></kwd>
<kwd lng="en"><![CDATA[Mycelial fungi]]></kwd>
<kwd lng="en"><![CDATA[bioreactor operation]]></kwd>
<kwd lng="en"><![CDATA[Ganoderma lucidum]]></kwd>
<kwd lng="es"><![CDATA[Cultivo biotecnológico]]></kwd>
<kwd lng="es"><![CDATA[cultivo sumergido de hongos]]></kwd>
<kwd lng="es"><![CDATA[exopolisacáridos]]></kwd>
<kwd lng="es"><![CDATA[Hongo miceliar]]></kwd>
<kwd lng="es"><![CDATA[operación de biorreactores]]></kwd>
<kwd lng="es"><![CDATA[Ganoderma lucidum]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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